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Introduction of Scientific Research Center

1.Brief Introduction of Development

In May, 1999, the 4thHospital of Hebei Medical University concentrated all departments’ scattered research instruments and purchased a lot of advanced equipments to equip the modernized Scientific Research Center. In October, 2000, after expert assessment and argumentation, Scientific Research Center was approved for “Hebei Provincial Key Laboratory of Cancer Gene’s Diagnosis, Prevention, and Treatment”, and assessed “Hebei Provincial Top Key Laboratory” many times. In November, 2008, after the evaluation and audit of expert group organized by National Administration of Traditional Chinese Medicine, Scientific Research Center was assessed “Tertiary Laboratory of National Administration of Traditional Chinese Medicine”, and became the first modernized laboratory with national qualification in Hebei Province.

2.Development Scale

The center now has 10 full-time researchers, 3 technicians. 3 among them bear senior professional title, 4 bear medium-grade professional title, 3 bear junior professional title, and 3 technicians; 2 of them are doctoral supervisors and 3 master’s supervisors. In recent years, as laboratory’s support unit, the hospital continuously put large amount of funds and effort into laboratory’s construction. The center has large-scale modernized equipments such as high throughput DNA sequencer (Life Technologies), multi-functional imaging analysis system (BioTek), flow cytometer (B&D), laser scanning confocal microscope (ZEISS), fluorescence microscope (Nikon), and fluorescentquantitative PCR device (ABI), etc. The center has operation platform that simultaneously accommodating 20 persons, and equipped with conventional experimental instruments.

In order to satisfy scientific research’s needs in east area, under the strong support from hospital leaders, as well as the close cooperation of Infrastructure Construction Department, Medical Equipment Department, and Logistical Support Department, etc.,the hospital continuously put large amount of funds and effort into laboratory’s construction. Scientific Research Center in east area was officially put into use on April 6th, 2016. Scientific Research Center in east area covers an area of 400 square meters. Now there are 3 cell culture rooms, 1 bacterial culture room, 1 nucleic acid operation experimental area, 1 protein operation experimental area, and 1 sample storage area within the department. The center has large-scale modernized equipments such as fluorescence microscope (LAIKA), fluorescentquantitative PCR device (ABI), upright microscope (LAIKA), multi-functional microporous plate detector (TECAN), tissue embedding device (LAIKA), etc., which satisfy basic experimental requirements of cytology, bacteriology,pathology,molecular biology, etc. The center has operation platform that simultaneously accommodating 20 persons, and equipped with conventional experimental instruments.

3. Work Task of Scientific Research Center

Scientific Research Center focuses on basic research for application, mainly carries out the work in fields such as tumor immunology, tumor biotherapy, oncomolecularbiology, tumor gene diagnosis, treatment and development of anti-cancer traditional Chinese medicine, etc., has established scientific research platform for different specialties, undertakes the hospital’s all experimental tasks of many state-level, province-level, department-level scientific research projects and postgraduate projects that under study, shoulders cancer prevention and treatment base’s scientific research tasks in cooperation with other associate organizations, pays great attention to the transformation of achievements of scientific research, how has gained 2 national invention patents.

In order to build rational talent team, the laboratory also pays great attention to strengthening academic communication, sends some of its staff to attend academic conferences of different levels every year, invites researchers from statescientific research facilities, colleges and universities, hospitals of USA, Japan, UK, etc., for communication and study.

4. Department’s Goal of Development and Overall Positioning

Based on the research direction of oncobiology behavior and its molecular mechanism, anti-cancer traditional Chinese medicine, cancer biotherapy, cancer resource and information management, our department carries out high-level cancer fundamental research and applied basic research, explores possible methods to postponing, repression or reversion of process of tumor cancerization and development, provides theoretical basis for cancer prevention, early diagnosis and treatment. We do our best in building laboratory into a domestic leading professional cancer prevention and treatment research center with the concentration of cancer basic research and clinical treatment.